The evolution of competition in innovation resource: a theoretical study based on Lotka–Volterra model

This research uses the Lotka–Volterra model to analyse the competition of innovation resource between two enterprises and studies the dynamic effects of environmental changes through the change of model parameters. The research finds that there are three possible results of the competition in innovation resource. That comprises ‘crowding out effect’, ‘unstable equilibrium’ and ‘stable equilibrium’. The results of competitive evolution are determined by enterprises’ interaction parameters. However, the natural growth rates, the initial resource possessions of both enterprises and the amount of regional innovation resource have a significant impact on the evolution of competition.     

Cost analysis of plasma-derived factor VIII/von Willebrand factor versus recombinant factor VIII for treatment of previously untreated patients with severe hemophilia A in the United States

Background: Inhibitor development to factor VIII (FVIII) hemophilia therapy results in increased complications and substantial economic costs. The SIPPET study, the first randomized controlled trial to compare the immunogenicity of plasma-derived FVIII (pdFVIII)/von Willebrand factor (VWF) and recombinant-DNA-derived FVIII (rFVIII), demonstrated higher inhibitor rates in previously untreated patients (PUPs) treated with rFVIII than in PUPs treated with pdFVIII/VWF.

Objective: To quantify the economic impact of treating PUPs with pdFVIII/VWF vs rFVIII.

Methods: An Excel-based clinical and economic model was developed from a US healthcare payer perspective and run over a 5-year period. The analysis utilized a cohort approach to model patient treatment and outcomes over a monthly cycle to quantify differences in costs of FVIII, bypassing agents, and hospitalizations for serious bleeds. Rates of high-titer inhibitor development were obtained from the SIPPET study. Patients developing high-titer inhibitors were treated with immune tolerance induction (ITI). Patients who developed low-titer inhibitors and those who did not develop inhibitors continued their usual FVIII treatment. Patients who were successfully treated with ITI returned to FVIII treatment, while unsuccessfully treated patients received bypassing agents. Total costs per treated patient were estimated and a one-way sensitivity analysis was conducted to quantify the impact of parameter uncertainty on the model outcomes.

Results: Total cumulative costs per patient over 5 years were $834,621 for pdFVIII/VWF patients and $1,237,163 for rFVIII patients, representing a total saving of $402,542 per patient over the 5-year period, for an average annual saving of $80,508 per patient.

Conclusions: Based on data from the SIPPET study, this analysis found that initiating FVIII treatment in severe hemophilia A PUPs with pdFVIII/VWF has the potential to offer substantial cost savings to healthcare payers, amounting to a one-third reduction in costs.     

江苏省生态农业与生态旅游业耦合研究

[目的]目前我国正处于关键的经济转型期,生态农业和生态旅游业作为生态文明建设的重要产业之一,其耦合发展对于存进产业结构优化升级具有重要作用。[方法]通过构建生态农业与生态旅游业指标体系,采用灰色关联法计算江苏省生态农业与生态旅游业的关联度,进一步通过耦合协调度模型分析两者的协调程度。[结果]生态农业系统与生态旅游系统中的旅游经济、旅游资源和旅游价值的关联度分别为0.719,0.673和0.621,大小顺序分别为旅游经济旅游资源旅游价值,而生态旅游系统与生态农业系统中生态系统、经济系统和社会系统的关联度分别为0.687,0.700和0.626,大小顺序分别为经济系统生态系统社会系统,耦合作用均分别为较强、较强和中等。2012~2016年江苏省生态农业和生态旅游业耦合度处于磨合阶段,但一直在增加,同时耦合水平经历了初级协调发展水平到中级协调发展水平的过程。[结论]江苏省生态农业和生态旅游业的耦合发展仍有进步的空间,今后应加强耦合发展机制,推动两大耦合产业走向更深更广的发展领域,促进生态文明建设,同时保证生态产业的可持续健康发展。     

Research collaboration model in academic social networks

ABSTRACT

This paper proposes a hybrid collaboration recommendation method that accounts for research similarities and the previous research cooperation network. Research cooperation is measured by combining the collaboration time and the number of co-authors who already collaborated with at least one scientist. Research similarity is based on authors’ previous publications and academic events they attended. A weighted directed graph is built to discover new collaborators by using direct and indirect connections between scientists. Moreover, a consensus-based system is built to integrate bibliography data from different sources. The experimental results show that our method improves the recommendation performances over other methods.     

Attitudes,norms and difficulties underlying road sharing intentions as drivers and cyclists: Evidence from the Czech Republic

Cycling-inclusive urban planning is attracting attention worldwide because of the environmental, health, economic, and transport benefits inherent to cycling from the individual and the societal perspectives. The Czech Republic is one of the emerging cycling countries that are trying to promote and support cycling, but cycling mode shares are low because of the poor quality of the scarce infrastructure and the psychological barrier of the perceived lack of safety when cycling in mixed traffic. This study takes a multimodal approach based on the Theory of Planned Behaviour and focuses on the factors underlying the willingness to share the road from the perspective of cyclists and drivers: positive attitudes toward cycling, positive attitudes toward cyclists’ behavior, social norms toward cycling and anxiety to share the road. A web-based questionnaire was tailor-designed and administered in the Czech Republic via social networks, web forums, and the Civinet network, and a hybrid bivariate-ordered model tested the behavioral framework. Results show that the willingness to share the road as a cyclist or as a driver relates positively to positive attitudes towards cycling and cyclists’ behavior, and negatively to the anxiety of sharing the road. Moreover, mediator effects are observed and a clear relation emerges between the experience on the road as both a cyclist and a driver on the willingness to share the road as a cyclist. Lastly, results show that the factors underlying road sharing intentions are related significantly to gender, travel habits, and perceived personal and infrastructure-related barriers to cycling.     

基于双重约束的区域耕地整理适宜性评价研究

[目的]科学合理的适宜性评价是确保耕地整理能够有效开展的前提条件,同时对于我国的耕地保护与粮食安全保障也具有极为重要的意义。[方法]该研究首先选取可以反映区域耕地整理适宜性的指标因子,然后参考胡学东提出的约束条件评价模型,引入区域生态安全和社会经济双重约束,对研究区域在双重约束下的耕地整理适宜性进行评价,并通过K-Means聚类法将研究区域的耕地整理适宜性分区进行合理划分。[结果]生态安全约束和社会经济约束对区域耕地整理适宜性水平具有重大影响,高生态安全约束与高社会经济约束会降低耕地整理的适宜性,低生态安全约束与低社会经济约束会提高耕地整理的适宜性。[结论]引入生态安全约束和社会经济约束后,可以在一定程度上反映山地区域在社会经济与生态安全双重约束状态下的耕地整理适宜性情况,耕地整理适宜性评价结果更加符合当地实际情况,约束条件评价模型可以更加合理准确地对处于约束条件下的耕地整理适宜性进行评价,是对耕地整理适宜性评价方法的丰富与完善。     

The sweet smell of advertising: the essence of matching scents with other ad cues

New technologies enable practitioners to communicate scents in advertisements on various media. The current research examines the importance of matching scent cues to the advertised product, and the joint effect of scent and other cues such as colour on consumer responses to advertising. A 4 × 2 experimental design was conducted, where participants (N = 603) were presented with scented colour print advertisements. Three hierarchical responses were measured: emotional response, attitude, and purchase intention. Findings reveal that higher congruence between scent and the advertised product heightens positive consumer response. Furthermore, this research stresses the significant joint effect of scent and colour cues, and supports the incongruence approach, suggesting that combining scents that are poorly congruent with other sensory cues enhance consumer response. Practical and theoretical implications are discussed.     

新疆西北部农户种植决策的Logistic模型分析*——以伊犁河谷察布查尔县为例

[目的]农户种植决策是诱发农业结构调整的微观基础,研究农户种植决策的影响因素,不仅有利于了解农业种植结构,也对该区域推进和深化农业结构调整,实现农业产业化、现代化具有重要的意义。[方法]文章基于新疆察布查尔县21个行政村228户农户的问卷调查数据,应用Logistic模型,从农户家庭特征、个体特征、生产特征及收入特征等4个方面实证分析了影响农户种植决策的主要因素。[结果]对农户种植决策行为影响显著的因素有家庭总人口、耕地面积、地形部位、总收入等,其中,耕地面积和地形部位对农户种植意愿有显著正向影响,而家庭总人口和总收入对农户种植意愿有显著负向影响;常年从事农业劳动人数、户主文化水平、地块位置、地块总数以及对于农业技术服务态度没有通过检验,无法得出这几个变量与农户种植决策之间的关系。[结论]影响农户种植决策的因素除耕地面积、总收入、家庭总人口及地形部位外,还会受到政策、农户自身种植习惯、农业技术等影响,农户对农业技术知识的匮乏是影响该县农业结构调整的主要原因     

A systematic mapping study on enterprise architecture mining

Enterprise architecture allows companies to deal with digital transformation through the proactive presentation and alignment of business and IT in a holistic manner. One important challenge is EA modelling since it is time-consuming (thus expensive), error-prone, and biased owing to experts’ subjective opinions. This challenge might consequently be addressed through automatic EA modelling. We conducted a systematic mapping study to classify and evaluate the research concerning EA mining proposals developed specifically for TOGAF and Archimate. After analysing results, we concluded that the research field is not sufficiently mature and further research on EA mining is necessary.     

基于效应的随机灰规划模型和应用

为了解决同时含有随机因素和灰色因素的不确定规划问题,通过结合区间灰数所属区间两个端点的随机性,给出随机区间灰数和随机区间灰函数的定义,提出了随机灰规划模型。通过综合效应函数理论用随机变量期望值和方差综合量化表示灰数所属区间的两个端点值。应用该理论对综合量化后的两个端点值继续进行综合量化,从而将随机灰规划转化为确定型规划问题。应用遗传算法进行求解。通过综合效应函数的理念,综合随机变量的期望和方差,同时综合区间灰数的区间因素,将随机灰规划数学模型转化为确定型规划模型即基于效应的随机灰规划模型。通过选取不同的综合效应函数,得到了关于不同决策意识下的随机灰规划的最优解。这个方法可为决策者进行不确定决策提供参考。